Indications & Usage
Cefixime is a cephalosporin antibacterial drug indicated in the treatment of adults and pediatric six months and older with Uncomplicated Urinary Tract Infections, Pharyngitis & Tonsillitis, Acute Exacerbations
of Chronic Bronchitis, Uncomplicated Gonorrhea.
Dosage
Cefixime Capsules are available for oral administration in the following dosage strength: Capsules provide 400 mgof cefixime as trihydrate. These are off white to yellow color granular powder filled in size
’’0’’’ hard gelatin capsules, Purple cap white body
Side Effects
Gastrointestinal - Several cases of documented pseudomembranous colitis were identified in clinical trials. The onset of pseudomembranous colitis symptoms may occur during or after therapy.
Hypersensitivity
Reactions - Anaphylactic/anaphylactoid reactions (including shock and fatalities), skin rashes, urticaria, drug fever, pruritus, angioedema, and facial edema. Erythema multiforme, Stevens-Johnson syndrome,
and serum sickness-like reactions have been reported.
Hepatic - Transient elevations in SGPT, SGOT, alkaline phosphatase, hepatitis, jaundice.
Central Nervous System - Headaches, dizziness, seizures.
Hemic and Lymphatic System - Transient thrombocytopenia, leukopenia, neutropenia, prolongation in prothrombin time, elevated LDH, pancytopenia, agranulocytosis, and eosinophilia.
Abnormal Laboratory
Tests - Hyperbilirubinemia.
Other Adverse Reactions - Genital pruritus, vaginitis, candidiasis, toxic epidermal necrolysis.